Nanoparticles, due to their nanometric size and unique properties, offer innovative solutions to improve the treatment and diagnosis of various types of cancer. Here is an overview of the most promising applications, supported by cutting-edge research.
Iron oxide nanoparticles: potential for breast, liver, and glioblastoma cancers
Iron oxide nanoparticles (also known as SPIO or SPION) are being studied for their ability to enhance the effectiveness of magnetic hyperthermia treatments. This technique involves injecting these nanoparticles into the tumor or into the bloodstream (when functionalized with a targeting agent), followed by activation using an external magnetic field. This process generates heat, leading to the destruction of cancer cells.
A study by Inserm indicates that this approach could be particularly effective against breast and liver cancers, two pathologies where current treatments sometimes remain insufficient. (Inserm)
SON specializes in providing nanomaterials dedicated to this application. SON has the capability to functionalize nanoparticles, particularly SPIONs, with dual functions. This enables iron oxide nanoparticles to be attached to both tumor-targeting agents and therapeutic agents. As a result, these nanomaterials can:
- Navigate toward the tumor
- Destroy diseased cells via the therapeutic agent
- Eliminate cancerous cells through magnetic hyperthermia
The goal is to eradicate cancer cells while preserving healthy tissue as much as possible.
SON is not a drug manufacturer but a nanomaterials supplier. If you are interested in this technology and wish to accelerate your research using our products, do not hesitate to reach out to us.
🔗 Discover our SPIONs and functionalized nanoparticles by following the links.
Gold nanoparticles and photothermal therapy for prostate cancer
Gold nanoparticles are attracting growing interest due to their biocompatibility and ability to absorb infrared light. In oncology, they are used for photothermal therapy, a treatment that targets cancer cells while minimizing damage to healthy tissue.
A study published in Nature Nanotechnology reports promising results for prostate cancer treatment. When exposed to laser light, these nanoparticles generate localized heat capable of destroying tumor cells. This approach could improve current treatments by reducing side effects. (Nature Nanotechnology)
SON has worked on the connection between gold nanoparticles and detection. The company has developed specific gold nanoparticles, including some shaped like nanoflowers, allowing for the exploitation of gold’s optical properties at the nanoscale.
🔗 Explore our gold nanoparticles by following this link.
Inorganic nanoparticles to enhance radiotherapy for head and neck cancers
Metal-based nanoparticles, such as those composed of hafnium or platinum, are being integrated into radiotherapy protocols to improve its effectiveness. When injected into the tumor, these nanoparticles amplify the effects of X-rays, thereby increasing cancer cell destruction.
Clinical trials conducted in France by Nanobiotix have shown encouraging results for the treatment of head and neck cancers. This approach allows for a reduction in the necessary radiotherapy doses, thereby limiting side effects for patients.
Another study published in The Lancet Oncology confirms that the use of these nanoparticles could also benefit other types of cancer, including brain tumors and sarcomas. (The Lancet Oncology)
Conclusion
The application of nanoparticles in oncology is opening new perspectives for the treatment of various cancers. From photothermal therapy to radiotherapy adjuvants, these innovations have the potential to revolutionize cancer care by making treatments more targeted and less toxic.
As clinical trials progress, nanoparticles could become an essential component of future cancer treatment strategies. Today, on February 4th, World Cancer Day, we felt it was essential to share these promising developments—offering hope to patients, their families, and all of us. 🎗️